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Coma Science Group Data Description

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Contents

SPM8 Processed data prefixes

T1: structural, anatomic data

st
Definition
c1, c2, c3
SPM8 normalized segmentation
m
normalized volumes
wc1, wc2 wc3
images after normalization
sw1, 2 3
smoothed normalized images
swc1
voxel based morphometry (VBM) studies

MD: Mean diffusivity

Represents the increase of overall molecule displacement and several kind of anisotropy indices

MD = \langle \lambda \rangle = \frac{\lambda_1 + \lambda_2 + \lambda_3}{3}

Provides good discrimination between VS/UWS and MCS patients.


FA: fractional anisotropy

Quantify the level of disorder of oriented structures in the tissue

FA = \frac{\sqrt{3( (\lambda_1 - \langle \lambda \rangle )^2 + (\lambda_2 - \langle \lambda \rangle )^2 + (\lambda_3 - \langle \lambda \rangle )^2)}} {\sqrt{2(\lambda_1^2 + \lambda_2^2 + \lambda_3^2)}}

Used to characterize the extend of white matter loss in VS/UWS patients


Disorders of Consciousness (DOC)

VS
Vegetative State
UWS
Unresponsive Wakefulness Syndrome
MCS
Minimally Consciousness State

Generalized Ordered Weighted Aggregations

A GOWA M on a set of positive real numbers \lambda_1, \lambda_2, \dots,\lambda_n is a map defined by:


M_{w,p}(\lambda_1, \lambda_2, \dots,\lambda_n) = (\sum_{j=1}^{n}w_{j}\theta_{j}^{p})^{1/p}

where  w_1, w_2, \dots, w_n is a collection of weights satisfying  w_j \in [0,1] \and \sum_{j=1}^{n} w_j =1, p is a parameter such that p \in [-\infty, \infty], \theta_j is the jth largest of \lambda_j. This operator is a generalized weighted average on the set of input re-ordered data.

Table summary

Field Mean
A ID: Identifier of the subject
B,C Subject's name
D Born date
E Etiology: Probable cause
F Possible accident date
G Examination date
H Initial classification of consciousness level
I Date difference between accident and examination (in days)
J Examination date
K Final Diagnose